not sure if others are having this problem but I tried both the Tascam US-122 and the M-Audio Audiophile and can't seem to get either to show up on my Mac while both work on my PC. The USB seems to be working as other devices are functional (Printer, scanner, etc...all of which are interfaced for software on OS 9 classic). I am running 10.2.8 and have tried the latest drivers....tech support for each device seems to be baffled, could this be a OS support issue (hopefully not since MAC support means $$$...)

Strange, haven't heard of this. Maybe try a new USB cable? If you're plugging into a USB hub, try freeing up a port to go directly into your Mac. Otherwise, ???

tried two different cables, and both ports...the ports are working....

I also have a G4 iMac with OS X 10.2.8 running Cubase SE and an M-Audio Audiophile USB. I have downloaded the latest drivers from the M-Audio web site, but can't try the earlier drivers because they don't download properly. The Audiophile works with midi in, but not out, and doesn't work with audio at all - I have to use the iMac's internal audio. However the Audiophile audio works with iTunes. I will try switching USB cables and see what happens....

I have a usb audiophile card,and it installed easily in 9.2,but I had loads of problems trying to install it into panther(computer crashing etc),I tried to download the latest drivers but it downloaded as a word document,so i thought to put it throught stuffit expander and it worked!!

Have you tried going to Audio MIDI setup and manually adding the interface, or are you expecting the system to automatically recognize it? Because I don't think that it will. Make sure you select "add new interface" from the menu in AMS, add whatever instruments are connected to it and route them to the correct ports, and see if that doesn't take care of it.

Some users seem to have troubles in audio MIDI setup in the 10.2.8 so it can be you drivers or OS related…

If you can, try in 10.2.6
And watch for Panther drivers… they will come (when???)

I have just downloaded a new driver from the M-Audio web site version 1.5.7f1 (only recently put there), and so far Cubase SE and my Audiophile USB seem to be working OK with my Mac OS X v10.2.8. Thanks for the suggestions.

I got tired of waiting for M-Audio to get their act together, so I went and got a Motu Fastlane midi interface. I had no problems what so ever, compared to a still not working midisport 2x2 running Panther on a G5.